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The Graceview Patient by Caitlin Starling

Margaret lives with a rare autoimmune condition that has destroyed her life, leaving her isolated. It has no cure, but she’s making do as best she can—until she’s offered a fully paid-for spot in an experimental medical trial at Graceview Memorial. The conditions are simple, if grueling: she will live at the hospital as a full-time patient, subjecting herself to the near-total destruction of her immune system and its subsequent regeneration. The trial will essentially kill most of, but not all of her. But as the treatment progresses and her body begins to fail, she stumbles upon something sinister living and spreading within the hospital. Unsure of what's real and what is just medication-induced delusion, Margaret struggles to find a way out as her body and mind succumb further to the darkness lurking throughout Graceview's halls. PUBLISHER: St. Martin's Press YEAR: 2025 LENGTH: 320 pages AGE: Adult GENRE: Horror RECOMMENDED: Highly Queer Rep Summary: No canon queer rep. *I...
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Animorphs Book 8: The Alien by K. A. Applegate

The Alien deals with isolation, uncertainty, and learning when/whether to trust. Ax must decide whether he's one of the Animorphs or just conveniently aligned. Ax tells the humans how Seerow's Kindness doomed their planet.

This book stands out for being the first real look at how differently Ax approaches everything as an Andalite. Its treatment of isolation while surrounded by friends and allies manages to be insightful without just treating Ax badly for not embracing the Animorphs as completely as they welcomed him. It's a delicate balance because too far in one direction would make it harder to trust them as a unit later in the series, but making him trust them too easily would make the conflict in this particular book seem pointless. It helps that there is a specific reason that Ax is hesitant to trust that goes deeper than just being uncomfortable, and I think it's handled well here.

A centaur-like alien with blue fur and stalk-eyes (Aximili the Andalite) turns into a human

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